I would say no: all detected partitions by VMware Tools will be mapped as an instance in the "Guest File System" metric. You cannot assign a different profile on- or simply ignore individual instances.
I think you can simply ignore these (or better: suppress them for a year). Over time, VCOPS will learn that these full P: drives are normal. Also, depending on your environment, do not expect your alert volume should be 0. My team only checks for critical 'infra' alerts (host, cluster, vcenter), an other team check things like full disk space or high amount of anomalies.